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MEMOIR 



ON THE 



DISCOVERY 



C*. 

OF A 



Wttifit gPHf¥lelJJt» 



For the cure and prevention of the Yellow Fever, Plague, Malignant and 

Pestilential Fevers- 



WITH DOCUMENTS, 



Authenticated by the results of successful experiments, performed by 
order of the Government and Authorities of the city of Havana* 



y 

BY JOHN JAMES GIRAUD, M. D. 

OF BALTIMORE. 

Formerly Surgeon to the Royal Marines, and subsequently Brevet Surgeon Major to the King 
of France, for the Admiralty of Cape Francais. 



Non quaerit aeger medicum eloquentem sed sanantem. 

SENEC— Epist 76. 



-A Medicine 



Of rare and prov'd effects, such as his reading 

And manifest experience had collected, 

For general sovereignty. SHAKSPEARE. 



Itx-T 



FRINTEr 



\ 



"HO^OCb 



MEMOIR 

ON THE 

DISCOVERY OF A SPECIFIC 

FOR THE 
YELLOW FEVER, PLAGUE, MALIGNANT AND PESTILENTIAL FEVERS, 

Authenticated by the results of successful experiments, performed by order of the Government 
and Authorities of the City of Havana. 



JL HE destructive effects of the Yellow Fever and Plague to suf- 
fering humanity, present considerations sufficient to excite the feel- 
ings of the dullest sensibility. The first of these terrible scourges 
appears to have fixed on the new world for the theatre of its ravages; 
to the American public, therefore, it must be a subject vitally inter- 
woven with the best interests of society. In some respects, it seems 
to have limited its devastations to particular points of the continent, 
and of the adjacent islands; but it has shown itself capable of spread- 
ing over immense districts, and of visiting parts previously secure 
from its pestilence; and so great has been the terror which it inspired, 
that the report of its progress disturbed the most distant solitudes, 
like the echoes of far off thunder rolling among the mountains. — 
Those who have had the melancholy privilege of witnessing its deso- 
lating career have represented it as 



"Labes qua scevior usquam 



Nulla fuit, nulla unquam aliis spectabitur annis." 

The physician whose feelings are not bound up in the profits of his 
eraft, will often in the daily routine of ordinary practice, behold 
scenes revolting to humanity; what will therefore be his sensations 
when he, for the first time, contemplates the soul-harrowing specta- 
cle at the sight of which the reflecting bystanders may almost regret 
being endowed with animation, and may envy the very stones under 
their feet for their insensibility. If the compassionate beholder 
should attempt to imbody in words his ideas of the disease, his de- 
scription will be like a sepulchral romance, and the depth and ten- 
derness of his feelings will interfere with the expression of them, 
as the sight becomes blind with tears. 



The Yellow Fever proves most fatal to those who are not acclimat- 
ed (if I may be permitted the expression,) to tl ose who h;ive travell- 
ed from distant parts, and have for the tirst time come within the 
sphere of the fever's malignant activity. Individuals who had pre- 
viously enjoyed the most uninterrupted health, are often the first vic- 
tims to the new Minotaur. They had perhaps been accustomed at 
home, to the most luxurious indulgence of their inclinations, and had 
never, in any serious degree paid the forfeit of their sensuality. They 
had probably heard of the dangers to which they would be exposed 
in the country they were about to visit; but it was only when they 
touched on the fatal shores that they became sensible of the truth of 
the accounts which they had disregarded. The first impression 
caused by the disease is abject despair — the bravest are cast down — 
the i eart endowed with almost deathless energy, becomes daunted, 
and the unhappy patient casts his eyes in vain regret to those scenes 
which have been sanctified by the name of "home." — 

"Moritur — et moriens dulces reminiscitur Argos!" 

If such be the effects of the desolating pestilence which we have 
been describing, it will be apparent that tie physician who, by pa- 
tient investigation, discovers aji antidote to its baneful ravages, will 
deserve the gratitude of mankind, and that his invaluable discovery, 
will carry bis name to posterity embalmed in the tears of succes- 
sive generations. 

If any faith can be placed in a series of experiments made to elu- 
cidate this subject — experiments which, during three successive 
years, were accompanied with the most satisfactory results, the dis- 
covery to which 1 allude has at length rewarded my laborious exer- 
tions in the cause of benevolence. The Medicine which 1 have 
compounded, is known in Havana chiefly under the name of 
"■specific," bin is usually termed "Doctor Giraud's Anti-pestilential 
and Specific Liquors for the cure and prevention of the Plague, Yellow 
Fever,* 4*c" These "Liquors" are limpid, inodorous, and tasteless, 
and possess neither purgative nor emetic qualities. Their radical 
virtue is to recal the secretions through their proper emunctories, 
and the crisis usually takes place by perspiration, urine. &c. 

THE political disasters of St. Domingo (where I resided for 
ten years) obliged me to take refuge in the United States. During 
the prevalence of the Yellow Fever, I had occasion to make some 
researches and experiments on the best means of obviating the ter- 
rible Epidemic, whic' had eluded all the resources of the healing art. 
In the year 1800, when this disorder was making the most alarming 
progress, I had the good fortune to discover its antidote, the effects 
of which were satisfactorily proven on 103 patients, attacked with 
the worst symptoms of the disease. The result of my experiments 
was the cure of 99 patients, authenticated by all the public authorities 

* In warm climates there exists what the inhabitants call maladie dupays, to 
which strangers are subject on their arrival, if they had not been previously 
acclimated. It is a bilious inflammatory fever which takes on a putrid type. — 
My specific is the sole preventive of this endemic complaint. 



of Baltimore. Still I was not perfectly satisfied with the Medicine, 
as it was then administered; it was attended with an inconvenience 
which it was absolutely necessary to obviate: it was necessary, in 
order to prevent decomposition, that the medicine should be freshly 
compounded every time a new dose was called for. The difficulty 
was to do away this perplexing inconvenience without diminishing 
the inherent virtue of the compound. To this subject I devoted my 
attention for a number of years; at length, after the most patient 
investigation, I brought the composition to a degree of perfection 
which entirely satisfies my mind as to its antidotal powers and its 
indestructible nature. It can be kept a number of years in glass or 
glazed earthen vessels, or even in wooden vessels, without under- 
going the slightest alteration, from the most intense heat or in any 
climate And at the same time it possesses the advantages of a per- 
fect arcanum, as its composition cannot be discovered by the best 
conducted chemical analysis. 

The Yellow Fever is cured by this "Specific" "quasi carmine 
magico." It constantly yields to its operation in 3, 5, and at far- 
thest 7 days, and the patient returns to his usual occupations two 
days after being cured. Its prophylactic virtue is such, that a single 
dose, taken at the commencement of an epidemic, will be sufficient 
to shield a person exposed to the disease, from its destructive effects. 

In the year 1820, I sent a large quantity of the "Specific" to 
Havana, by my agent, A. Martin, in order that experiments might be 
made, under the inspection of the Medical Faculty and Authorities 
of the Spanish government in that city, and the result has been en- 
tirely satisfactory to the Governor and Authorities. I have collected 
authentic Documents relative to the different experiments performed 
during a period of three successive years, by a committee of Phy- 
sicians appointed by government, and duly attested by the different 
authorities. These incontestible Documents prove, that my "Specific" 
has been eminently successful in the cure of the Yellow Fever; that 
it has been invariable in its beneficial operation on individuals of 
every temperament and of every nation; and that it has remained 
undecomposed, in all the variations of the seasons, and in every tem- 
perature of the atmosphere. All these Documents were forwarded 
to the government at Madrid. But the Spanish revolution, and the 
death of the Governor of Havana, (Gen. Mahy,*) at the moment 
when the government was on the point of purchasing my secret 
Medicine, destroyed the fruits of all my labours, and subjected me 
to a considerable pecuniary loss, after I had expended vast sums to 
further my object. 

It was mentioned above, that, during the prevalence of the Yellow 
Fever in Baltimore, 103 patients attacked with the disorder, were 
treated with my "Specific," and that out of that number, 99 were 
perfectly cured. As, during the epoch of the epidemic, great con- 
fusion reigned in the city, and the novelty of the extraordinary cures 

* It was by the order of Gen. Maht, that the experiments were made, and be 
was an eye witness to the great success of the Medicine in the various cases 
subjected to its influence. 



performed by the medicine, excited considerable attention on all 
sides, I thought proper to note down the names and dwellings of all 
the persons who were treated and cured under my management. I 
at the time published a list of those persons, the greater number of 
whom are still alive, and I here give the names, in the same order as 
before. 

We the subscribers, residents of the city of Baltimore do hereby certify, 
thai Doctor John J. Giraud attended us during the prevalence of 
the yellow fever, which raged in this city in the year 1800 when 
labouring under that disorder, and cured us of it by his judicious 
and salutary treatment — And to testify our persuasion of the truth, 
and efficacy of his mode of treatment, we have hereto given our sig- 
natures. 
William Walker, Light st. Mary Baker, Thames st. F. P. 

Ebenezer Black, Bridge st. O. T. Jacob Myers, 11 Water st. 
William Manro, Exeter st. Constant Anna Spark, York st. 

Jacob Brown, Ruxton lane. Caleb Hannah, Market space. 

Theresa Wilson, S. Howard st. 
Jo n David, Head of Market st. 
Richard Thornton, Public alley. 
Martin Bangot, 12 Howard st. 
Susannah Tyson, Lancaster st F. P 
George Wilson, S. Howard st. 
Nancy Weaver, Sugar alley, and 

my daug' ter. 
James Loopol, Lemmon alley, my 

wife. 
Joseph Thomas, Lancaster st. 
Veronica Usher, Staff alley, F. P. 

my daughter. 
Thomas Scott, Head of Baltimore 

street. 
Thomas Ford, 57 Apple alley, my 

boy. 
Joseph Hampton, Market st. F. P, 
Martha Thomas, Head of Balti- 
more st. 
Sarah James, 40 Causeway 
Peter Bennet, Happy alley, F. P> 
Ann Robinson, Wolf st. 






John M'Nier, Lee st. Federal Hill 
Nicholas Allen, Market st. F. P. 
George Hussy, Causeway, for 3 

persons in my family 
Jacob Miller, Jones st. O T. 
Conrod Bentzell, 21 Second st. 
Mary M'Uonnell, 35 Gay st. 
Isabella Freeman, 60 Gay st. 
George Adams, Strawberry alley, 

F. P. 
Stephen Moor, Hook's town road. 
Hraman Jarvis, Lee st Federal 

hill, for my son. 
Thomas Littlejohn, 6, F. P. for my 
I step-daughter, Market Space. 
James Cheyter, 59, Pitt st. for my 

wife. 
Richard Norris, Goodman st. 
Elizabeth Murry, Spear's wharf. 
Frederick Williams, Head of the 

Basin. 
John Brown 5 Spear's Wharf. 



James Childs, 59 Bond st. 

Elizabeth Lanaway, S. Howard st. Hugh Becker, Barrst. 

Thomas Henderson 
Matthew Taylor, Market space, 

for my wife. 
John Bond, S. Howard st. 
Sarah Park, Lexington st. and my 

sister. 
David Anderson, Gallows hill. 
Ann Fitsimmons, King George st, 
Mary Long, Pratt st. 



i Camden st. 
William Honman ) 

John Howard, Happy alley, F. P. 

James Robinson, Bond st. 

John Smith, Wolf st. F. P. 

Jacob Young, Happy alley. 

Hannah Thomson, Fleet st. 

Walter Johnson, 

William Jones, 41 



George st. 



-Matthew M'Clorian. Corner of 

Market and Fleet sts. F P. 
William George, Duke st 
L Jol nston, King George st. 
Polly Thomas, Duke st. 
Anthony Gill, J 
Joseph Abram. \ 69 Apple alley 
Simon Amborg ) 
Peter Boduoin, 67 Camden st. 
Charles Green, Head of Market st. 
Flora Trimble, Whiskey alley. 
John Ward, North st. 
Julianna White, German st. 
Catharine Welsh, Eutaw st. and 

my boy. 
Henrietta Forest, Dutch alley, my 

brother. 
Elizabeth M ushers, Strawberry 

alley 
Jacob Fisher, 69 ^ 
Williom Gardner, 70 \ Caroline st 
Peter Hall 80 S 



Joseph Thomson, North st. 
Helena Smith; Forest alley. 
Thomas Gardner, Waggon alley, 
Ann Sanders, 80, Apple alley. 
James Taylor, Washington st. 
Margaret Shaw, 70 Causeway. 
Peter Feekes, 72 Waggon alley. 
Ann Pasket, 29 Thames st. 
Charles Stewart, 75 Waggon alley, 

and my daughter 
Peter James, Happy alley and my 

wife. 
Rose Walker, do 
John Patterson, Argyle alley. 
John Robinson, near the Semina^ 

ry, my two daughters 
John Porter, > York st. Federal 
Martha Smith, \ Hill. 

John Slere, Lancaster st. 
Jacob Stephen, Rogers alley. 
William Smith, North st. 



STATE OF MARYLAND. 

City of Baltimore, to wit: 
Be it remembered, that on this twenty sixth day of March, m 
the year of our Lord, eig teen hundred and six, personally appeared 
before me the subscriber, Mayor of the city of Baltimoie, Dr. John 
J. Giraud, of the city aforesaid, a citizen of the I nited States, who 
being duly sworn on the Holy Evangelists of Almig- ty God, deposeth 
and saith, that in the year 1800, during the prevalence of the yellow 
malignant fever in the said city of Baltimore, he did make the dis- 
covery of a medicine, which he is thoroughly persuaded is a certain, 
and specific remedy for the cure, and prevention of that disease; that 
during the period of five years past, he has always administered it to 
such patients labouring under the above mentioned disease, as were 
committed to his care, and by means of it has affected their cure, 
generally in the course of eight days, by using the remedy in the 
commencement of the disorder, and before the application of any 
•ther; that from the happy and uniform effects, which have constantly 
attended it, he verily believes it to be a certain and specific remedy 
for the said disease, and that it will stand the test of time and expe- 
rience: And moreover that he the deponent is ready at all times to 
submit it to such trial, and proof, as may be required to establish its 
efficacy. 

In testimony whereof I have hereunto subscribed my name, and 

caused the corporate seal of the said city to be affixed, on the 

day and year first above written. 

THOROWGOOD SMITH. 
|Seal.] Mayor of the city of Baltimore 



8 

We the undersigned Merchants of the city of Baltimore, do hereby 
certify, that Dr. John J. Giraud, resident and practitioner of phy- 
sic, in the said city, for thirteen years past has always enjoyed 
general esteem and confidence; and we are of opinion, that his 
discovery of a Specific remedy for the Yellow Malignant Fever is 
far from being an imposition on the public; on the contrary, we 
deem him worthy of the greatest encouragement for the discove- 
ry; it being of the highest importance to the public welfare. 

ALBERT SEEK AMP, ANTHONY KIMMEL, 

EDWARD FENNEL, GEORGE REPOLD, 

MICHAEL KIMMEL, HENRY MESSONIER, 

LEWIS PASCAULT, JOHN BARRON, 

FRANCIS DUCHEMIN, P. A. GUESTIER, 

J. J St. MACARY, J. B. ALLEGRE, 

JOHN LATOUR, JOHN A. GUENNET. 
JOHN B. JAUFFRET, 

In the year 1806, my intentions were to render the discovery ot 
my "Specific" public. 1 wrote a treatise to that effect, embracing 
my remarks on the Yellow Fever, the Plague, Pestilential and Ma- 
lignant Fevers, and other disorders produced by a high temperature of 
the atmosphere. This work, which was to have been published by 
subscription, included a body of observations on the various phenom- 
ena that marked the progress of the epidemic on our continent I 
detailed the characteristic symptoms of the disease in its differ- 
ent changes and modifications, ascertained by careful observation at 
the bedside of the patient: after which I entered on the thorny 
question of the contagious nature of the epidemic; 1 then treated of 
its remote cause and its localities; finally I presented a series of 
analytical experiments, and a history of the effects produced on the 
disease by the different remedies usually recommended- — having ad- 
ministered them all in the most careful manner, without any favoura- 
ble result. Several considerations induced me to abandon my project 
of publication at that time; I had suffered considerable fatigue of 
mind and body, and I had not as yet improved my "Specific" to its 
present degree of perfection. I then (as I have already mentioned) 
devoted my exclusive attention to the subject of the "Specific" and 
gave it its present excellence. In consequence of its unprecedented 
success, during the epidemic which prevailed in Baltimore in 1819, 
I made a gratuitous offer of the "Specific" to the public, through 
the medium of the newspapers. I deposited" a certain quantity with 
the Mayor of the city (Edward Johnson, Esq.) to be delivered gratis 
to all the Physicians who should apply for it — I likewise deposited 
with Messrs. Laroque and Milhau, Apothecaries, a certain quantity, 
for the use of the public. In doing this, I was guided by those 
feelings of humanity, without which no man can lay claim to the af- 
fection and esteem of his fellow beings. I went as far as 1 was war- 
ranted by the interests of society, and the slightest attention to my 
own; to have published the secret of my "Specific" would not have 



9 

materially advanced those of the former, and would have snatched, 
from me the reward of my unwearied and health-consuming labours. 
Had I inconsiderately divulged my arcanum, several fruitless en- 
deavours would probably have been made to improve a medicine, 
with which 1 alone (who had devoted a considerable part of my life 
time exclusively to it) could have been perfectly acquainted Dab- 
blers in experiment, and interested speculators, would have exhausted 
their restless activity in adding to, or subtracting from, the power 
of its ingredients. — Although, in the end, their efforts would only 
have produced (in Shakspeare's language) "wasteful and ridiculous 
ex ■ , .ess'*— Besides (as has occurred in other well-known cases,*) 
perhaps some stranger would have claimed the merit of the dis- 
covery, regardless of the impartial law of the Legislator of Parnassus, 
"Palmam qui meruit ferat." 

My views were now to assure myself positively of the effects of 
the "Specific" in all the varieties of the disease, and in the changes 
effected on it by the different seasons and climates I turned my 
attention to the city of Havana, where the disease is endemic, and 
prevails more or less constantly during the year, but principally in 
the months of July, August, September and October? This season 
is usually the most fatal to newly arrived strangers, and it is a rare 
thing for those who have not dwelt in warm countries to escape, in 
the months of November. December, January and February, the 
Malignant and Typhus Fever which prevail, often assume the type 
of the Yellow Fever, especially when many strangers arrive Dur- 
ing the months of March, April, May and June, when the Remittent, 
Intermittent and Bilious disorders reign, they preserve a putrid or 
maugnant character, from which the inhabitants themselves are not 
exempt Moreover these diseases take on a different type during 
the rainy ana windy seasons, especially when the wind blows in one 
particular direction, or in a high temperature of the atmosphere. — 
And often, during the winter months, the Yellow Fever is disguised 
under the symptoms of other maladies, such as the Dysentery, 
Cholera, 4*c 

I have already observed, that in the year 1820, I sent a quantity 
of the "Specific" to Havana, under the agency of A. Martin, and 
I alluded to the authentic documents published on the subject of the 
experiments instituted under the inspection of the competent author- 
ities. The experiments were conducted during the whole of three 
years; and that they were crowned with perfect success is proved by 
the subsequent documents. 

* The celebrated Harvey, in his Lectures, explained his doctrine of the cir 
culation of the blood, some time before he published it to the world: but, as soon 
as the "monstrous innovation" was divulged, the merit of the discovery was 
contested, and some envious wretches even maintained that Hippocrates had 
been perfectly well acquainted with the circulation!! The immortal fame which 
has accrued to Jenner, for conferring his secret of vaccination on mankind, 
has been assailed from the same sordid motives. — But, as Junius said cf Lord 
Chatham: "Recorded honours shall gather round their monument and thicken 
ever them, it is- a solid fabric, and will support the laurels that adorn it.'* 

o 



10 

0FFTCIAL REPORTS.* 

[Translated from the Spanish.] 

Observations and experiments which were made by Physicians 
commissioned by the Protomedicato, Don Nicolas del Valle, Presi- 
dent of the Board of Health, by order of the government and the 
most excellent assembly, relative to "Doctor Giraud's Antlpestilen- 
tial Liquors for the cure and prevention of the Yellow Fever, Plague, 
&c." (in the possession ot Mr. A. Martin) in order to ascertain its 
virtues and utility. Communicated by the said Physicians to the 
Tribunal of the Board of Health. 

The following is the attestation of Fr. Francisco Pacheco, Presi- 
dent and Surgeon Major of the National Monastic Hospital of S'an 
Juan de Dios. 

I do hereby certify that Mr. A. Martin began to administer the 
"Specific" for the Yellow Fever in this hospital, on the 4th of Sep- 
tember, to the patients labouring under the Yellow Fever or Black 
Vomit, as ascertained by Doctors Jose Bohorquez, and Pedro An- 
dreu, who were appointed for that purpose 

From the moment the patients began to use the "Specific" its good 
effects were immediately perceived; this was not only during the in- 
flammatory and first period of the malady, but during the whole state 
of the disease, which from the administration of the "Specific" gra- 
dually got better, until about the fifth day, when perfect health was 
restored For the purpose which it may concern, I give the present, 
in the most faithful city of Havana, 17th Oct. 1820 

Signed, FR. FRANCISCO PACHECO. 

In virtue of the appointment which your excellency has thought 
proper to make, and of the official letter received from the Regent, 
Don Jose Piz irro, commissary under government, to observe the 
application and effects of the "Specific" for the cure of the Yellow 
F*ever or Black Vomit, we have personally attended, in the street 
of Obra-pia, No 12, conjointly with A. Martin, a number of pa- 
tients attacked with the symptoms which designate the Yellow Fever 
or Black Vomit, in the first period of the disease, and having follow- 
ed and observed the administration of the said '-Specific" to the said 
patients, we observed that the disease was cured the third or fourth 
day after using the "Specific. ' This was effected by a copious dis- 
charge of urine and perspiration, the cure terminating by a slight 
purgation. 

To the patients in the Hospital of St. John of God, with the same 
disease and symptoms, it has proved equally beneficial as it did to the 
others. Notwithstanding these experiments, we did not consider 
them sufficient to induce us to declare our opinion of this "Specific," 
it was our intention not to reply until we should have made new ex- 
periments in another season, in order that we might form a correct 

* All the official papers, reports, letters,&jc. contained in the subsequent pages, 
are extracts from original authentic documents, in the Spanish language, which 
were sent by the governor of Cuba to the court of Madrid; a copy of which, 
signed, countersigned a«-d approved by the authorities of the city of Havana, 
was shew.) to the consuls of fhe^different nations in Baltimore, and was authen- 
tically recognised by the Chevalier Bernabeu, Spanish Consul. 



11 

idea of it. As, however, we have received a new official letter from 
the aforesaid Commissary Regent, requesting us to certify what we 
had observed concerning the "Specific;" we comply by sending yoa 
the following note 

We take the liberty to request your excellency to order that the 
new experiments to be performed next year, be made when the fever 
rages with its greatest intensity, and then, by making new obser- 
vations, we shall be enabled to judge of the true value of the "Spe- 
cific" and to pronounce decisively on its good effects. — This is all 
the information which we can at present, and incompliance with our 
trust, give your excellency; however your excellency can act ac- 
cording to the light that is within your mind — this we send you in 
answer to the official letter which you transmitted to us. God pre- 
serve your life many years! 
Havana. Oct. 26, 1820. 

(Signed) Dr. JOSE BOHORQUEZ, 
Dr. PEDRO ANDREU. 
The President of the Tribunal of the Board of Health, Dr. Don 
N. del Valle, hiving thought proper (when the most excellent Assem- 
bly recommended to his attention the Anti-pestilential Liquors) to 
trust the examination, and to the high celebrity and extensive practice 
of Doctors Jose Bohorquez and Pedro Andreu, — these two phy- 
sicians expressed their opinions in the written testimony of the 2* th 
October, 1820, in favour of the "Specific, " and they said that, con- 
sidering the number of patients cured in presence of Dr. Juan Bau- 
tista Bocruz, delegate of the Tribunal of the Board of Health, sup- 
ported by Dr. Pedro Andreu, they decide in favour of, the great eft 
ficacy of the said "Specific" communicated to the Board, the 18th 
October, 1820. 

The constant success of the "Specific," and the unqualified com- 
mendations, bestowed on it by unbiassed judges, excited the rancor- 
ous jealousy and quprulous snarimgs of certain envious wretches, 
who did their utmost to mildew the harvest of a well-deserved celeb- 
rity Nothing material interposed, however, to cloud the brilliant 
success of the invaluable medicine: on the contrary, the cures were 
multiplied on all sides — and it was soon made known that 150 pa- 
tients attacked by the destructive fever, were snatched by it from the 
jaws of a certain death, as if by enchantment. A remedy endowed 
with such admirable properties, and presenting such unquestionable 
proofs of its power in annihilating the horrible scourge which had 
paralyzed commerce, and presented the most unsurmountable ob- 
stacles to the effective display of national resources, — merits the 
most profound attention from Governments, and from every class of 
individuals, who are in effect the greatest suff- rers from its ravages, 
and who ought therefore to rejoice in the success of an antidote to 
its further progress. 

The above remarks were suggested by Jie subject of the follow- 
ing address: 

Gentlemen of the Board of Health of the City of Havana, 
Mr. A. Martin has understood that the document he addressed to 



12 

ihe government, together with that to prove that he has in his pos- 
session a "Specific" for the Yellow Fever, have been transmitted to 
the two Physicians who compose a part of the Poard of Health, in 
order that they should give their respective opinions; these physi- 
cians, as was expected, spoke favourably of the beneficial effects of 
the said "Specific;" however, notwithstanding the experiments made, 
the Memorialist has learned that certain envious persons have ex- 
pressed some doubts, which may possibly frustrate the favourable 
expectations entertained by him concerning those who may be at- 
tacked with this terrible disorder: he thinks it therefore his duty 
again to request the honourable members of the Assembly, to ap- 
point the most distinguished physicians, who may attend in person to 
all the experiments they have a right to exact from the memorialist, 
in the cure of the Yeilow Fever; Impressed with this consideration, 
and being anxious that the experiments be instituted forthwith, your 
memorialist most humbly entreats you to name the physicians whose 
duty it shall be to certify the result of the experiments he shall per- 
form, in order that no further doubt remain of t e favourable result 
of the "Specific." 

The application of what is enclosed is tor the information of the 
Board, who will be pleased to communicate it to the gentlemen whom 
they shall appoint for the purpose of attending to the exact adminis- 
tration of the "Specific." All this the memorialist requests, as in 
duty bound. 

Havana, Dec 18, 1820 Signed, A. MARTIN. 

Official documents from the Professors of the Proto-medicato 
(Royal Medical College) in conformity with the notice of Doctors 
Jose Bohorquez and Pedro Andreu 

Relying on the information which these two physicians have given 
to the Protomedicato concerning the utility of the "Specific" for the 
Yellow Fever, in the possession oi A. Martin; in order that the pub- 
lic may not be deprived of said medicine until the following sum- 
mer, A. Martin is hereby permitted to use and continue the adminis- 
tration of the anti pestilential medicine for the cure of the Yellow 
Fever, on the advice of another physician whose opinion he must 
Consult. Rut, that from this time until the above mentioned period, 
the Protomedicato remain sure with regard to the preservation of 
the public health, we request of you doses of said "Specific," to 
analyze it, in order to become acquainted, not with the simples of 
which it is composed, but to see whether the effects of the medi- 
cine, although beneficial for the cure of the Yeilow Fever, might 
not in the main be followed by injurious consequences. In the 
event that this should be the case, it will become our duty to declare 
it. We agree with the observations made by the above mentioned 
gentlemen of the faculty, concerning the "Specific," as we repose 
unlimited confidence in them, and appoint them superintendents of 
this affair. God preserve your life many years! 

Havana, Oct. 26, 1820. Signed, Dr. NICHOLAS DEL VALLE, 

Dr. JUAN PEREZ DELGADO, 

frentlemen of the Commission of the Most Excellent Meeting. 

Mr. JOSE ^IZMiKO and LLDO, 
Mr. MARIANO HERNANDEZ. 



IS 

In virtue of the commission of the Board of Health, and at your 
request in the name of the most excellent assembly, I have visited, 
in company with Mr. A. Martin, a number of patients presented to 
me by him, to whom he administered the "Specific" in his pos- 
session for the Yellow Fever The result I have communicated 
to you and to the Regent Physician. Since that time, I visited seve- 
ral patients affected with that disease, at the request ot said Mar- 
tin; and those are the patients mentioned in the report of Doctor 
J. B. Bocruz, which speaks most favourably of the invaluable 
"Specific." God preserve your life many years! 
Havana, Nov. 20, 1820. 

Signed, Dr. PEDRO ANDREU. 

Report to the Board of Health. 
Mr. Jose Pizarro — Since the 24th of October last, until the 19th 
instant, 1 visited in company with Mr. A. Martin, several sick per- 
sons, to whom he administered the "Specific" which he has in his 
possession to cure the Yellow Fever or Black Vomit. In these 
patients I perceived the salutiferous effects of the "Specific." Of 
this you may judge by the subjoined list which I sent you, and by the 
official letter which you desired me to return, &c. This is all I can 
communicate to you at present. God preserve your life many 
years! 

Havana. Aug. 20, 1820. 

Signed, JUAN BAUTISTA BOCRUZ. 

List of persons whom I visited in conjunction with Mr. A Martin, 
and to whom he administered the "Specific" for the Yellow Fever. 

Mrs. Maria Carman, wife of Mr. Juan de Castro, in the house of 
Mr. Antonio Rodriguez, in front of the Marine Auditors, commenc- 
ed to use the "Specific' 1 on the 24th October, and re-embarked 12th 
November;she came here with the convoy of the frigate La Pronta. 

Mr. J.uan del Rio, Lieutenant of the National Marine Frigate, 
Commander of the sloop of war The Galga, in the house of Madam 
Lachaisey in Obrapia street, No. 12; entered the 2d of November, 
and departed the 7th of the same month. The captain of the brig 
Conception, Mr. Antonio Qiiintero, entered the same house on the 
7th, and departed the 1 6th November. Sebastian Perez, marine of 
the same vessel, entered the same house, the same day, and departed 
thp 9th of the same month. Pierre Michel, of the brig Minerva, 
entered the same house the 7th and departed the 9th November. — 
Santiago Marentin of the same brig, entered the 8th, and departed 
the 16th November. The captain of the vessel Sardo Jason, entered 
the same house, the 8th and departed the 11th of November. Val- 
entin Francisco Fontana, nephew of the same captain, entered the 
13th and departed the 16th November. Andres Costa, entered the 
14th and departed the 17th November. Francisco Batavmo, second 
captain of the bri^ Jason, entered the 16th September, and departed 
the 19th November. 

All these individuals were visited by Doctor Andreu and myself; 
they were all restored to health, and those few whose fever was in 



14 

aay measure obstinate, were relieved at farthest in forty-eight hours, 
the greater part of them from thirty-six to forty-eight hours, and 
several from twenty-four to thirty hours. In all I have observed a 
secretion of the urine and perspiration, and their convalescence was 
fey no means laborious. 

Signed, JUAN BAUTISTA BOCRUZ. 

I have visited in a private house, a great many individuals attacked 
with said malady (the yellow fever,) and who have been cured in my 
presence by Martin, and with the "Specific;" all saying that the 
effects in all have been favourable. God preserve your life many 
years! 

Havana, March 23, 1821. 

Signed, FR. FRANCISCO PACHECO. 

The principal merchants of the city of Havana, perceiving with 
sentiments of deep.sorrow, that the crews of vessels to their con- 
signment, for the most part fell victims to the destructive epidemic 
which raged in that port, drew up and presented a petition to gov- 
ernment, praying that Mr. A. Martin be permitted to administer ex- 
clusively the 'Specific" for the Yellow Fever. This petition was 
complied with without the slightest hesitation; and all vessels to the 
consignments of the said merchant*, (who composed the Chamber of 
Commerce of the city of Havana) having on board persons attack- 
ed with the Yellow Fever, have invariably been attended by the said 
Mr. A. Martin; and in 'every case the usual success has accompanied 
the administration of the said "Specific " 

Most Excellent Sir — We the undersigned, resident merchants in 
this city, to your Excellency respectfully state: That we see with 
unfeigned sorrow, a vast number of individuals of the crews of ves- 
sels that arrive at this port from Europe, consigned to us, carried off 
by that horrible disease, the Yellow Fever, in spite of the prompt 
and methodical administration of the medicines commonly used for 
this disease. 

We call your Excellency's attention to this subject, convinced by 
repeated successful experiments, that the "Specific" for the Yellow 
Fever, in the possession of Mr. A. Martin, administered by him with 
the assistance of a physician, operates more powerfully and effectu- 
ally against that dreadful malady than the method and medicines gen- 
erally adopted. 

We would not correspond to the confidence placed in us as con- 
signees, if in a case of such vital impoitance, we did not contribute 
to the diminution of the risk to which those persons under our care 
are exposed. This consideration prompts us to recommend the use 
of the above "Specific;" and although we could here relate a long 
list of cures effected by the timely application of said "Specific," 
and of the unfortunate result in cases wherein the ordinary medicines 
have been used, we omit a recital that would occupy too much of 
your Excellency's attention, which we beg leave to call to the princi- 
pal object of our solicitude. 

We, therefore pray your Excellency, as the authority of the 
province, and the most interested in its prosperity, to order in the 
manner which may be most proper, that Don A. Martin be author- 



15 

ized to administer the "Specific" with the assistance of a Physician, 
to every person belonging to vessels from Europe consigned to us, 
who may be attacked with Yellow Fever. 

Final!}', convinced of the singular virtues of that remedy, we feel 
bound in conscience to procure it in behali oi those unfortunate be- 
ings, who under the above circumstances have been consigned to 
our care and attention. 

It is a favour which we have reason to expect from your Excel- 
lency's goodness and justice. 
(Signed) Havana, February 7, 1822. 

Manuel Roig y Mila — Vila y Puig — JuanGuelly Ferrer — Manuel 
Presas — Narciso Pusarnisile — Antonio Pasqual y Soler — Juan Maria 
Melszet — Acebal, Pacheco y Ca. — A. Autrau — Blain, Aizpuruay Ca. 
Jose Maria Chacon — Juara, Gov y Ca - — Blakely y Pontinelly — Juan 
Cantegril — Antonio Font — Martin Lamy — Felipe A Canes y Ca. 
Antonio Rodriguez — Juan Soler — Juan Alba — Jose Anet — Castillo 
y Compa. — Benito Vila — Aureau — Antonio de Frias y Compa. — Juan 
Bta. Ycara — John Carrera Dmosutt. 

Don Joaquin Jose Garcia, second Interpreter of the National Navy, 
by Royal appointment of the most excellent constitutional Council 
of this ^ity, and of the Board of Health, here certifies, that the fore- 
going translation is faithfully done from its original in the Spanish 
Language, to which 1 refer — Havana, March 19, 1822 — (Signed) 

JOAQUIN JOSE GARCIA. 

Certificate. 

I, John Warner, commercial agent of the United States of America 
for Havana, do hereby certify, that Joaquin Jose Garcia, whose sig- 
nature is affixed to the preceding instrument in writing, is a regular 
commissioned interpreter of this city, and that to his acts as such, full 
faith and credit is due. 1 also certify, that I know many of the 
Merchants signing the annexed recommendation to his excellency the 
Governor, and that they are Gentlemen of respectabilitj^. 

In testimony whereof, I have hereunto set my hand and seal of 
office, at Havana, this tenth day of April, in the year of our Lord one 
thousand eight ' undred and twenty two, and of the Independence of 
the said United States, of America, the iorty sixth. — (Signed) 

JOHN WARNER. 



* SEAL OF THE # 

<g,UNITED STATES. 5, 



One series of successful experiments, performed during the four 
seasons, with scarcely one ratal termination, had now convinced the 
authorities of the miraculous effects of the "Specific." In spite of 
this, it was surprising and painful to behold numbers of soldiers who 
fell sick of the fever on their arrival at the port mercilessly consigned 
(o the Hospital and treated according to the common routine of prac- 



16 

tice, that is, invariably with ill success. Humanity exclaimed loudly 
against this wanton sacrifice of the life of fellow beings; till at length 
a petition to Government was drawn up by Mr. A Martin, which was 
attended with the complete triumph of the "Specific." 

Tohis Highness the Superior and Political Chief. 

Don A. Martin, with profound respect, to your excellency exposes: 
that he sees with feelings of the deepest regret the departure of hun- 
dreds of people from this life, (whose existence would have been of 
the, utmost importance to their respective countries and families,) by 
the desolating ravages of the Yellow Fever. The Deponent alludes to 
the great number of persons that perish in the Military Hospital of 
St. Ambrosio, in which prompt assistance and the most opportune 
remedies are necessary to arrest the fatal progress of this terrible 
disease. 

For more than two years the Petitioner has been anxiously labour- 
ing to obtain the unqualified acknowledgement of the advantageous 
effects of Dr. Giraud's Antipestilential Specific, in his possession. 
More t an fifty respectable Merchants, and crews of vessels con- 
signed to them in this port, have presented themselves before you, 
praying your Excellency to cause the "Specific" to be administered 
to all persons in this Hospital, who may have come under their 
consignment, and were affected with the disease. Various public 
documents (which have never been refuted) evince the numberless 
cures performed by the "'Specific" within the last two years. 

The experiments made, and the documents written in the year 
1820, corroborate this truth officially On the 10th Sept. 1821, the 
Physicians appointed to that duty by the Royal Medical College, con- 
cluded those experiments which the Deponent has published, as well 
as their favourable opinions of the "Specific." Wishing however, 
to convince themselves thoroughly this present summer, the experi- 
ments were repeated under the immediate superintendence of four 
Physicians officially appointed for this purpose, and in all their cases, 
the "Specific" has been invariable in its success. Under these cir- 
cumstances, it must be as painful to your Excellency as it is to him 
who has the hononr of addressing you, to behold so many vic- 
tims to the disorder, who might have been snatched from a prema- 
ture death, by the timely administration of the antidote. 

He offers himself to administer his "Specific" publicly in presence 
of all the Physicians of this capital, that the beneficial effects may 
become apparent to all; and that the sincerity with which he haa 
always treated this most important affair, may strike the most obtuse 
perception. 

He therefore prays your Excellency to cause a certain number of 
individuals sick of the Yellow Fever, to be placed in a ward express- 
ly allotted for the purpose [these patients must be in the first period 
of their disease, without having received any remedy] and that under 
the superintendence of the Physicians appointed, they will be treated 
with the "Specific," which the Deponent has in his possession to cure 
the Yellow Fever— The results will definitively decide its virtues. 



17 

The petitioner is perfectly convinced that thousands of lives will 
be spired if the use of the "'Specific" be continued, a consequence 
which will necessarily follow from the satisfaction which this public 
exhibition will cause. 

All that your Petitioner hopes is, that your Excellency may de- 
termine in favour of a remedy which promises so many advantages to 
the world at large, and to the individuals of this Island in particular, 
whose welfare and happiness your Excellency is so solicitous to 
promote. 

Havana, May 5, 1822. 

To his Highness the Governor. 

(Signed) A. MARTIN. 
'-Havana, May 6, 1822. 
Let this petition be sent to the Senior Physician of the xMedical 
College, who after maturely considering its contents, will determine 
whatever may appear to him just and according to law, or inform me 
exactly whatever he may judge the right course to be pursued. 
Signed, MAHY, 

Governor of Havana. 
Most Excellent Sir — As during the two last years, 1 have permit- 
ted the Petitioner to administer the "Specific" before the Physicians 
appointed by the Medical College; and the experiments which were 
made having produced effects favourable to humanity, lean have at 
present no objection that in the Hospital of St. Ambrosio a ward be 
appropriated for patients with the Yellow Fever, and that the Peti- 
tioner be entrusted with their treatment without the assistance of any 
other physician than the one who shall pronounce on the nature of 
the disease. For the accomplishment of which, all the patients will 
be assembled together, and thus we shall realize the certainty of the 
"Specific." 

Havana, May 7, 1822. 

To His Most Excellent Highness. 

Signed, LORENZO HERNANDEZ. 

"Havana, May 7, 1822. 
Having considered the preceding informationof the first physician 
of the Medical College. Let Don A. Martin present this petition 
and decree to the Military Hospital of San Ambrosio, and the person 
appointed will afford the necessary assistance without delay. All 
the physicians of that Hospital must be made acquainted with this 
business, and it is my wish to be made acquainted with the results. 
Signed, MAHY." 

Havana, May 8, 1822. 
Let this petition, under the protection of the First Physician of 
the Medical College, and recommended by his lordship, the C iptain 
General, be sent to the Intendant Inspector of Hospitals, to o )iain 
what is requested in it. 

Signed, PIN1LLOS. 

Havana, May 8, 1822. 
The Inspector ©f the Hospital will execute the superior decrees 

3 



18 

above: appointing a ward or hall for the purpose designated; and h^ 
will give a full relation of the results. 

Signed, GARCIA* 

The copy of the preceding decrees exhibited by Don A. Martin, 
and which I now return to him, is conformable to its original; and 
in order to comply with what has been requested, 1 affix my signature 
in this ward, called Guadaloupe, without the walls of Havana, the 
20th January, 18:3. 

Signed, JUAN DE MERED. 

We, the undersigned, do hereby attest, that D. Juan de Mered, 
by whom the preceding testimony is given, is authorized by the 
king to effect such deeds, and he uses said power, with general ap- 
probation. To all his testimonies entire faith and credit is therefore 
due. In witness whereof we hereunto place our signatures 
Signed, MANL AYEDA, 

TJOH FRAN. RODRIG, 
Havana i January 20,1823. MIGL GARCIA MAYETO. 

I, the undersigned^ French Consul in Legation to the Island of 
Cuba, certify that the above signature of Garcia, Inspector oi the 
Hospital of San Ambrosio, is correct. 
Havana, March 24, 1823. 

Signed, J. M. ANGELUCY. 

To give an idea of the manner in which the experiments were 
conducted, I here present some cases, which will be considered suf- 
ficient; the treatment having been invariable in all. The lollowmg 
three cases were taken in critical days ol the season, when the heat 
of the atmosphere was at its height 

On the lltli of August, at one p. m. we visited for the first time, 
Juan Maria Viel. (French sailor on board the frigate Flora,) of a very 
robust constitution, sanguino bilious temperament; had been taken 
ill the preceding night with a high fever, face and lips very much 
inflamed; eyes slightly ophthalmic, and pained on moving them; 
headach; pain in the loins, arms and thighs; tongue dry, red and 
bilious; breathing painful; heat, aridity and dryness of the skin, which 
was of a bilious colour. 

The patient had never previously been in this country, nor in any 
other visited by the Yellow Fever; for which reason, and on account 
of the intensity of the heat, (thermometer 89 ) we pronounced the 
disease Yellow Fever, and we informed Don A. Martin that he 
might administer the "Specific." 

In the evening, a little cessation of the fever; but the pulse still 
full and hard, some moisture on the tongue; little urine, but tur- 
bid; little perspiration; other symptoms the same. 

At night greater diminution of the fever; abundant perspiration} 
alleviation of the headach, and other pains. 

On the 12th, in the morning, less fever; pulse softer and less full; 
tongue moist and almost clean; breathing easier; cessation of all pains 
but in the eyes which remained (as also the face) very much inflam- 
ed; urine thick and abundant. 



19 

At 12 o'clock the fever continues abating; alleviation of the 
cephalalgia; less urine; more perspiration; adnata jaundiced; tongue 
inflamed on the borders; bilious in the centre; belly soft and without 
pain; although the patient had no passage for twenty-five hours. 

At night, considerable diminution of t urine; neither thirst nor per- 
spiration; pulse fuller and a little more frequent; involuntary sighs, 
muscular lassitude; extreme debility; no passage. 

On the 13th, the third day of the disease, in the morning, the same 
state as in the preceding night, some moisture on the skin; no passage 
for forty-four hours 

At 12 o clock, same symptoms; apyrexia almost complete; little 
increase of heat; some appearances of debility. 

At night, complete apyrexia; greater muscular action; inflammation 
in the face and eyes almost gone; eyes showing a more biltous dispo- 
sition; abundant perspiration; less sighing; more serenity; tongue 
moister; less red, and still charged; copious bilious passage. 

On the 14th, in the morning, fourth day of the disease, pulse and 
heat natural; skin and eyes same; no pains; tongue charged; more 
muscular activity; four bilious passages; cessation of t e "Specific." 
He took a purge composed of ten grains of jalap, and one ounce of 
manna, dissolved in barley water; in tiie afternoon had five bilious 
passages; some debility; little appetite. 

On the 15th, the fifth day of the disease, he begins his convales- 
cence; still some slight jaundice; more appetite. 

On the 17th, cured; went on board the seventh day after the attack 
of the disease. 

The 3d of September, in the morning, we visited Augustin Suidro, 
a Frenchman, officer on board the bri? Sophia, twenty four years of 
age; constitution robust; disposition sanguino-bilious; taken ill the 
prec -ding night with a high fever, hard pulse, redness in the face and 
eyes, woich latter painful on motion; headac ; pain in the loins; 
tongue dry, red and bilious; skin dry and hot; painful sensibility in the 
stomach; general weariness. These symptoms, together with the 
extraordinary heat of the season, his age and constitution, and his 
never having been in a place where the Yellow Fever exists, induc- 
ed us to pronounce it such, and the "Specific" was administered to 
him. 

At 12 o'clock, the symptoms continue; some perspiration; in the 
afternoon, abatement of the fever; eyes a little clearer; tongue a 
little moister; alleviation of the pains; less sensibility in the bowels; 
little perspiration; little urine 

The 4th, in the morning, second day of the disease, from twelve 
o'clock at night, abundant perspiration; diminution in the other symp- 
toms; pulse softer; apyrexia almost complete; urine abundant; no 
evacuation. At 12 o'clock in the morning, some alleviation; in the 
evening, high fever; pulse fuller and harder; headach as before; 
face and eyes more inflamed; suppression of urine and perspiration; 
intense thirst; dryness and aridity of the skin. 

The 5th, in the morning, third day of the disease; increase of the 
fever and all t e symptoms; diminution of strength; heaviness; invol- 
untary sighs; little more urine; no evacuation. At 12 o'clock same 



state; in the evening, a slight diminution in all the symptoms was per- 
ceived, in the skin especially; it being less dry and less burning. 

The 6th, in the morning, the fourth day of the malady; considera- 
ble diminution of the fever; urine and perspiration abundant since 
the preceding night; the tongue moister. and cleaner; less redness in 
the eyes; no heaviness; no evacuation; in the evening apyrexia near- 
ly perfect; no pains; excretions more profuse; no evacuation. 

The 7th, in the morning; complete apyrexia; little appetite; took 
the purge as above; in the evening two evacuations; convalescence. 

On the 8th, in the morning, sixth day of the malady; good appe- 
tite; natural gayety; went onboard cured. 

The 11th of September, we visited in the evening Juan Saracin> 
a Frenchman; constitution very robust; fifteen years old; sanguine 
temperament; taken the preceding night with a very high fever; pulse 
full and hard; severe headach; pains in the loins and extremities; 
dryness, aridity and heat in the skin; intense thirst; tongue scarlet and 
bilious; face very much inflamed; eyes almost ophthalmic; urine very 
scarce from the commencement; drowsiness. This patient, whose 
symptoms designate the Yellow Fever, began immediately to take the 
"Specific." 

The 12th in the morning, second day of the disease, some dimi- 
nution of the fever observed; he had twice passed water in a small 
quantity; symptoms of the same intensity. Second visit in the morn- 
ing; same situation. In the evening sensible diminution of the fever; 
little urine; equal vehemence in all the other symptoms; belly cos- 
tive. 

The 13th, third day of the disease; more diminution of the fever; 
no thirst; tongue a little moist; but still bilious; skin red, but the co- 
lour disappearing to yellow; some heaviness; little urine. Second 
visii in the morning, pulse less hard; less full and less frequent; pros- 
tration of strength; involuntary sighs; eyes injected; little urine; five 
bilious passages in the evening: apyrexia; heaviness 

The 14th, in the morning, fourth day of the disease, apyrexia; 
tongue moister; skin rather soft: natural heat; more urine: less heavi- 
ness, increase of strength. In the evening, apyrexia; abundant per- 
spiration; urine as in health; slight headach; eyes of a more natural 
colour; cessation of pains in the loins and extremities; slight heavi- 
ness. 

The 15th, in the morning, fifth day of the disease; apyrexia; 
pulse soft; profuse perspiration; urine as in health; tongue moist and 
loaded; eyes clearer. In the evening, some state of alleviation 

The 16th, sixth day of the disease. Same state; took the above 
mentioned purge. In the evening he had four bilious evacuations. 

The 17th, convalescence; good appetite; natural gayety. 

The 18th, cured and went on board. 

On the 14th of August, in the morning, we visited for the first 
time Francisco Dwimer, belonging to the Dutch brig Correo, of a con- 
stitution most athletic; twenty-two years of age; sanguineous con- 
stitution; taken the preceding night with the symptoms of Yellow 
Fever. The 17th died at half past eleven at night, at the beginning 



21 

of the fourth day of the disease * The same day, the 14th, in the 

morning, we visited Joseph Mollicer, belonging to the same brig, fifteen 
years old: constitution robust, sanguino-bilious; was taken sick with 
all the symptoms of Yellow Fever. On the 18th, at half past two in 
the morning died, seven days after the commencement of the at- 
tack.* 

The 1 1th of September, we visited Carlos Duale, Frenchman, 
officer of the ship Two Stars, twenty-two years old; robust consti- 
tution; sanguino-bilious temperament, whs taken ill the preceding 
night with all the symptoms of Yellow Fever. The 17th, was cured 
and went on board. 

Tiie 12ti of Sep ember, we visited in the afternoon Joaquin Olive- 
ra, Portuguese, on board the brig Buen-Jin. Sound constitution; 
thirty five years old, and bilious disposition; lately arrived at this 
port; on the same day he was taken ill with the most violent symp- 
toms of Yellow Fever. The 17th was cured, and the 18th went on 
board, five days after the attack. 

The 14th of September, we visited in the afternoon Don Sebastian 
Silva, Portuguese, captain of the ship Minerva, of a sound constitu- 
tion; thirty-two years old; bilious habit. This patient was taken on 
the same morning very ill, with very strong symptoms of Yellow Fe- 
ver. The loth, he was cured and went on board. r. 

The 21st of September, in the evening, we visited Bernardo Viol, 
French sailor, on board the ship Two Stars, twenty-one years old; ro- 
bust constitution; sanguino-bilious habit: took sick the preceding day 
with the strongest symptoms of the Yellow Fever. On the 24th, was 
cured and weat on board. 

Havana, Feb. 18, 1822. 

Signed, Dr. LUIS GENEBRIERA, 

Dr. PEDRO ANDREU. 

1 here present a small number of cases which occurred in a very 
critical, though advanced season, all of which were cured in the most 
satisiactory manner; the longest treatment only occupying five days; 
and each case was well characterized. 

* To those who were perfectly well acqainted with the virtues of the "Spe« 
cific," the death of anyone to whom it had been administered, was a matter 
of considerable surprise; in as much as out of two hundred and more patients, 
who were treated exclusively by this remedy, only four cases ended mortally. 
This fatal termination was attributed, not to the intensity of the disease, but 
to the bad constitution of the individuals, and the complication of diseases under 
which they laboured. 

The death of the two patients mentioned above, caused so much astonish- 
ment, that researches were made to discover, if possible, what might be the 
cause of the fatal event. These two fellows, in their anxiety to shield them- 
selves from the attack of the pestilence (the very idea of which is so awful to 
the imagination,) imprudently followed the advice of some officious person, 
who perhaps thought he was rendering the greatest service; they swallowed, on 
going to bed, a large bowl of strong hot tea made stiff, with one quarter of 
its volume of brandy. The disease declared itself in both of them the same 
night. The supposed prophylactic which they took, is one of the greatest ex- 
citers of this disease; so that the inflammatory and nervous state which imme- 
diately declared itself was borne rapidly to the highest degree of intensity; 
fhereby rendering the "Specific" perfectly inert. 



22 

September 9th, the Captain of the Portuguese brig Buen-fin — 10th, 
Jaques, sailor of the brig Aimiable Julia — 2 1st, Lwutenait of the 
ship Neptune — 21st, Alexandre* Ferrera, sailor of the r'ortu^uese ship 
Minerva — 23d, Mancoz Ckauvel, Spanish sailor— I lib, Peim Sane, 
sailor of the ship Three Sisters — 25th, Antonio, sailor of the Fortunate 
Star—* 25th, Peter, sailor of the ship Neptune — 26th, Panckit Biscay- 
en, sailor — 27th, Prevost, sailor of the Fortunate Star. 

The experiments made at Gibraltar, during the most violent epoch 
of the prevalence of the plague, were sufficient to prove mcontesti- 
bly the prophylactic virtue of this " Specific," against that horrid dis- 
ease. The reason why it was not used as a curative, was the difficulty 
experienced in procuring a sufficient quantity of it; but is it* propuy- 
lactic virtues were recognized on all hands, no doubt was entertained 
of its curative qualities. 

All the experiments of which we have spoken in these pages, 
were performed in such a manner as to leave no vestige of doubt on 
the unbiassed observer. They were made during all the seasons and 
months of the year, and from one year to anot <er, on patients of dif- 
ferent nations and constitutions, so as to entitle the "Antipestilenhal 
Liquors" to the appellation of the exterminator of those horrors, 
that had scattered death and dismay over the finest regions of tne 
globe, 

"Horrors that would the sternest mind amaze, 
Horrors that Daemons would be proud to raise!" 

The result of the experiments performed during three successive 
years with this "Specific," has been gratifying even beyond the hopes 
that had been entertained, since out of the number of three hundred 
and sixty-eight patients afflicted with the Epidemic, three hundred 
and sixty have, by its means, been snatched from the jaws of 
death. 

1 felt some misgivings at first to the title of "Specific," conferred 
on the Medicine — as most nostrums are distinguished by that specious 
name; but on mature reflection, I could not find a term more appli- 
cable. Indeed, the medicine, on account of its peculiar virtues 
which have been so well authenticated, merits the distinctive appella- 
tion of "Specific," better than many of the remedies which "medical 
dogmatists" have exclusively honoured with that title. I feel confi- 
dent, that when the virtues of my valuable Specific shall be univer- 
sally acknowledged, it will take its place among the most beneficial 
eompounds of the Materia Medica Envious and self-opiniated men, 
will, no doubt, endeavour with all their malignity, to dim the lustre of 
its celebrity; they will do their best to silence the applause which has 
every where hailed its brilliant success; or they will perhaps call on 
the public to put no trust in ephemeral fame, and announce with pr©- 



23 

phetic voice, the ruin of the author and hi? remedy. But their hopes 
for that event will have the same chance of being gratified, as the ex- 
pectations of the simple countryman of Horace. 

"Rusticus expectat dum defluat aranis; at ille 
Labitur et labetur in orane v«lut»ilis cevuiu. : " 



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